ChemInform Abstract: Intramolecular Alkene Carboamination Reactions for the Synthesis of Enantiomerically Enriched Tropane Derivatives.

摘要

The attempt to transform noncyclic alkenyl substrates into tropane derivatives fails.The method proceeds generally without racemization and can be applied to the preparation of the MK‐801 analogue (XIII) in optically active form.